Head to Head

ALNY vs KRYS: which is the better buy in 2026?

On Alexandria's Compass, Alnylam Pharmaceuticals has the edge with a 77/100 score versus 52/100 for KRYS. Here is how they stack up, factor by factor.

Alnylam Pharmaceuticals

NASDAQ:ALNY

Edge
77/100 Compass
FavorableAccumulate$31.3B

RNAi's first profitable platform company is trading near its 52-week low while its pipeline has never been broader or more valuable.

Full ALNY analysis

Krystal Biotech, Inc.

NASDAQ:KRYS

52/100 Compass
NeutralAccumulate$9.8B

VYJUVEK is the proof of concept that gene therapy works as a topical, repeatable product. The pipeline is the real prize.

Full KRYS analysis

Factor by factor

FactorALNYKRYS
Revenue Growth3535
Profitability5256
Valuation3758
Momentum2470
Theme Purity9958
Moat4950
Catalysts9963
Market Position5248

Get head-to-heads like this, free

Join the Alexandria e-letter for Compass verdicts, earnings intelligence, and the contrarian calls the crowd misses. Twice a week, no noise.

Free forever. Unsubscribe anytime. We never share your email.

Frequently asked questions

Is ALNY or KRYS the better buy in 2026?

By Compass Score, Alnylam Pharmaceuticals (NASDAQ:ALNY) edges it at 77/100 versus 52/100 for KRYS. Both scores update weekly and reflect a contrarian, forward-looking read, not a recommendation.

How does Alexandria compare ALNY and KRYS?

Each company is scored 1-100 on eight factors: revenue growth, profitability, valuation, momentum, theme purity, moat, catalysts, and market position. The Compass Score is the composite, and the comparison below shows where each name wins factor by factor.

Compass Scores are proprietary editorial research from publicly available data, not investment advice or a recommendation regarding any security. Rankings update weekly.