Head to Head

ALNY vs SYK: which is the better buy in 2026?

On Alexandria's Compass, Alnylam Pharmaceuticals has the edge with a 91/100 score versus 90/100 for SYK. Here is how they stack up, factor by factor.

Alnylam Pharmaceuticals

NASDAQ:ALNY

Edge
91/100 Compass
True NorthAccumulate$27.5B

RNAi's first profitable platform company is trading near its 52-week low while its pipeline has never been broader or more valuable.

Full ALNY analysis

Stryker Corporation

NYSE:SYK

90/100 Compass
True NorthAccumulate$124.9B

Mako is becoming the standard, not the upgrade. The robot installed base is the moat everyone underestimates.

Full SYK analysis

Factor by factor

FactorALNYSYK
Revenue Growth3535
Profitability5157
Valuation3863
Momentum1744
Theme Purity9999
Moat4944
Catalysts9999
Market Position5247

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Frequently asked questions

Is ALNY or SYK the better buy in 2026?

By Compass Score, Alnylam Pharmaceuticals (NASDAQ:ALNY) edges it at 91/100 versus 90/100 for SYK. Both scores update weekly and reflect a contrarian, forward-looking read, not a recommendation.

How does Alexandria compare ALNY and SYK?

Each company is scored 1-100 on eight factors: revenue growth, profitability, valuation, momentum, theme purity, moat, catalysts, and market position. The Compass Score is the composite, and the comparison below shows where each name wins factor by factor.

Compass Scores are proprietary editorial research from publicly available data, not investment advice or a recommendation regarding any security. Rankings update weekly.