HRMY vs SEPN: which is the better buy in 2026?
On Alexandria's Compass, Harmony Biosciences Holdings, Inc. has the edge with a 90/100 score versus 89/100 for SEPN. Here is how they stack up, factor by factor.
Harmony Biosciences Holdings, Inc.
NASDAQ:HRMY
A cash-gushing rare disease franchise trading at 6x forward earnings while the market waits for pitolisant to escape narcolepsy.
Full HRMY analysisSepterna, Inc.
NASDAQ:SEPN
First credible oral GPCR pipeline since the gold rush, with Novo Nordisk paying the bills and a 2026 Phase 2 readout that resets the floor.
Full SEPN analysisFactor by factor
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Frequently asked questions
Is HRMY or SEPN the better buy in 2026?
By Compass Score, Harmony Biosciences Holdings, Inc. (NASDAQ:HRMY) edges it at 90/100 versus 89/100 for SEPN. Both scores update weekly and reflect a contrarian, forward-looking read, not a recommendation.
How does Alexandria compare HRMY and SEPN?
Each company is scored 1-100 on eight factors: revenue growth, profitability, valuation, momentum, theme purity, moat, catalysts, and market position. The Compass Score is the composite, and the comparison below shows where each name wins factor by factor.
Compass Scores are proprietary editorial research from publicly available data, not investment advice or a recommendation regarding any security. Rankings update weekly.